Gosh, Pablo.....the questions people ask here really make me think about my own language.
You can "open up" a business, or a nightclub, and it would be OK, but a bit "casual".....but even here, the word "up" is not necessary - you can "open" a business. In fact, most of the times English speakers say "open up" they could say "open".
There are some things which you definitely do NOT "open up"....you open the door,or the window, you open your eyes, or your heart. You open a discussion.....
A policeman may bang on your door and demand that you "Open up!" Or a surgeon may "open you up". You can "open up" to people, rather than be aloof or shy or dishonest.
So, I think "open up" is used to denote something general rather than specific. The surgeon "opened me up", rather than the surgeon opened my abdomen, or he opened my chest, or he opened my hip joint.
My advice - avoid using "open up".