The meaning is the same. The only difference is 'what are you up to tonight' is more casual. I wouldn't for example say this to my boss.
October 26, 2016
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They're the same :)
2nd is a little more casual/informal
October 27, 2016
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"What are you doing tonight?" is the more formal of the two. However, the second one can also imply that you are going to do something "no good" or naughty.
October 28, 2016
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