In English, you conjugate (change) the word "to be" according the subject. The following mean all "to be":
I am
you are
he/she/it is
we are
you are
they are
There's a similar change in German, but there are more forms instead of am/is/are:
ich bin
du bist
er/sie/es ist
wir sind
ihr seid
sie sind
The meaning is always the same, these are different forms of the verb "sein". Just as you don't say in English "you am" or "he are", you always use the appropriate form in German.