"Un mot" is "A word".
"La parole" is "The speech"
(The words / Les mots) are made with letter(s). They can be read, and pronounced.
(The speech / La parole) is the way to speak, to produce sounds and using words. The speech / La parole cannot be read.
I can write this message without using my speech/ma parole (my voice), but I have to use words to be understandable. If you was in front of me, and if I was using my voice to explain the difference I would be using my speech/ma parole (my voice), and I would also be using words to be understandable.
Do you see the difference now ?
Sometimes "La parole" can be a synonym of "Le discours" (which is also translated as "The speech" in English). In this case it's more about "an idea", "an opinion", something symbolic. For example "the speech / le discours / la parole) of someone in a religious book, or a political party.
"La parole de Dieu"
"Un mot" can also be "A note" about a little piece of paper with something written on it.
"Je t'ai laissé un mot sur la table"
:)