When “guess” is used to mean something like “think”, it indicates a lack of confidence in one’s answer, while “think” indicates a higher level of confidence. Example: A: “Who is your favorite singer? B: Adele, I guess. But I don’t know for sure. Patsy Cline is great too.” Compare this to: A: “Who is your favorite singer? B: “Definitely Adele. I think she has the best vocal range and the most nuance.” Another example: A. Do you want to go to the movies? B. I guess. Here, “guess” indicates a lack of enthusiasm.