で
1) at, in
わたしはとうきょうではたらく (私は東京で働く) = I work in Tokyo.
2) by
わたしはくるまでつうきんする (私は車で通勤する) = I commute by car.
3) because of, due to
しあいはあめでちゅうしになった (試合は雨で中止になった) = The game was called off due to rain.
4) by, in (time)
こうじはあと2~3にちでおわる (工事はあと2~3日で終わる) = The construction will be over in the next few days.
5) on
わたしはかのじょとでんわではなした (私は彼女と電話で話した) = I talked to her on the phone.
て
1) and
わたしはべんきょうをしてつかれた (私は勉強をして疲れた) = I studied and got tired.
2) (て at the end of a sentence -> ask, request, order)
でんわして (電話して) = Call me, むかえにきて (迎えに来て) = Come pick me up.
They can be used for many meanings, but I hope this helped... =)