Mostly the same!
'Heading back' is more colloquial, but they are both informal (formally, we might say 'returning home').
One difference is 'heading back' refers to leaving a temporary place (restaurant, friend's house, etc.). It would usually be used to mean 'walking/driving back to one's house'.
'Going back' could mean leaving a temporary place, OR travelling further (from a trip).
Ex. My mom is GOING BACK to Puerto Rico to visit her family.