If this is a statement all on it's own, it probably refers to whether you can "count someone in" or not. That is are they going to participate or join in. "I'm so in." would you usually have the emphasis on the word "so", indicating that the person can definitely be counted in or will eagerly participate.
If someone said "We are thinking of hitting the clubs tonight. We heared that there may be some celebrities around. Are you coming?" Someone might respond "I'm so in."