Is it okay to say ‘nice to e-meet you’ when you talk on chat application like Line?
The same as the subject.

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Sure, why not? Sounds cute. I love a good pun.

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Yes, it's ok.. But people normally say "nice to meet you". I guess "e-meet" can be used as a joke? I mean, if you want to seem more of a playful person..

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That's clever, but I have never heard that. Most people say "Nice to meet you," just as in face-to-face conversation.