You mean here using those verbs in relation to a problem or a matter in particular,because otherwise 'address' and 'handle ' could have other distinct meanings.
'to address'
means to deal with a problem or a matter by thinking carefully about it and doing things to improve the situation.
'to handle'
involves taking action as well to deal with a situation ,a person or anything that is seemingly difficult
'to deal with'
is both handling and addressing a situation .
It is thinking about it and then taking the required action .
'to cope with'
is almost the same meaning as 'to deal with' and it has to be a difficult situation.
As you see they are somehow close in meaning and in many times synonyms and could be used interchangeably.