you can say:
如果是'他半开玩笑地弄了她,你可以说:he played a prank on her // he played a practical joke on her // he played a trick on her
那个孩子喜欢搞恶作剧 that child is always up to mischief // that child always plays pranks on people
孩子们在搞恶作剧可以翻译作 The children are up to mischief // The children are playing a practical joke on someone(on someone 强调着某人成为受恶作剧的对象)