Use "amount of" before uncountable nouns such as "Homework, water, money,..." a substantial amount of money
use "a great deal of..." before uncountable nouns "A great deal of effort"
"Big effort" is not wrong but informal.
Use Number before countable nouns such as " people, animals, pens,..." A large number of people rushed into the street.......
or " The number of people interested in Facebook is increasing"