Without more context, it's hard to give a definitive answer. However, here's one meaning that no one else has mentioned. In visual art, a "study" is a series of works that explores and investigates the nature and use of a particular visual component. Thus, an artist might embark on a "study of motion" or a "study of light". In this context, a "blue study" would be a study of the color blue and the artist might experiment with different shades of blue in a series of pictures (paintings, drawings, photographs, whatever). Usually, the "study" is in a single medium (oils, acrylics, watercolor, pen and ink, photographs) but it could span across multiple media if the artist is so inclined. However, the phrase "a blue study" is perhaps less commonly used than "a study in blue".