what that this mean?: "She is game"
the context would be flirting

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"To be game" is informal and means "to be prepared or willing for smth".
For example:
I'm game for a try.
Is anybody game for some beer?
She's game for anything.

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she is willing and ready

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i'm game= estoy dispuest@ a..

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It's slang for someone expressing interest.  She is game = she is interested.  Is anybody game for some beer = is anybody interested in some beer.

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sorry, it is What DOES this mean