guilt is a noun, it means a strong feeling of sadness and shame when you do something wrong: he felt a great sense of guilt after losing his child.
also when someone brokes the law: the jury was sure of the defendant's guilt.
blame as a verb is to think that someone is responsible for doing something bad: the husband blamed his wife for the loss of their child.
also blame something on someone : don't try to blame me on this accident.
as a noun
get the blame for: mike always gets the blame for his brother's mistakes.
take the blame: you dont have to take the blame if u didn't do it.