furious

The simplest version is: 'very angry' or 'extremely angry'. A more natural expression that a native speaker would use is: 'in a fit of rage', 'uncontrollably angry'

fuuuuuuck! fuuuuck off ！（滚！ 此语超粗，女生误用，获bachelor及以上文凭者误用） motherfucker ! bitch ！ son of bitch ! bastard ! （混蛋！英国人喜欢用） bloody fool ！ （大傻逼）（说话带个bloody一般是在咒骂）

irritation