"In the sense that/of" is typically used to clarify the meaning of something one is trying to express.
Example:
That woman is hot in the sense that she as a fever, not that I think she's attractive.
You use "sense that" before a secondary clause ("she has a fever" in my example), and "sense of" when it's used before a verb ending in "ing". (example: "When I said his nose is running, I used the word 'running' in the sense of dripping, not of moving quickly.")