You are biased TOWARDS something, but you are prejudiced AGAINST something
But if you are simply stating that something is not neutral (but not indicating the direction of favour), either can theoretically be used. "The court was biased" "The appraisal was prejudiced". The adjectives are synonyms.
However, in modern usage, "prejudiced" has a fairly strong negative connotation in all common uses, whilst "bias" is a bit more flexible in how judgemental the connotation will be depending on the context