"sissy"what does it mean?
"-Oh, by the way the little marks, uh, that look like water spots...
I tend to stand too close to the urinal, so...
what you're seeing there is splash back"
"-You make sissy on your belt buckles?"
in tbbt ,Sheldon said "sissy" what does it mean? thanks!

Question

"sissy"what does it mean?
"-Oh, by the way the little marks, uh, that look like water spots...
I tend to stand too close to the urinal, so...
what you're seeing there is splash back"
"-You make sissy on your belt buckles?"
in tbbt ,Sheldon said "sissy" what does it mean?  thanks!

Answer

A sissy is an effeminate male. Your example doesn't make sense.
They are obviously substituting the word 'sissy' for piss(urine).

Answer

I had to read the script a few times for it to make sense. It seems that "make sissy" is a mocking way of saying "urinate". Is Sheldon putting on a country-hick accent when he says that?

"Make sissy" is hardly common English, so I doubt you'd see it anywhere else.

Answer

sissy means "delicate" or "weak"