Good memory, Jura! I'd forgotten about that story!
In the Sherlock Holmes story, victims are poisoned with a powder of an African root called Radix pedis diaboli (“Devil’s-foot root” in Latin). t seems it's best known for being mentioned in that story. I assume it's real, although I haven't yet found a reference to it that isn't about Holmes. Doyle was a doctor who usually liked accurate technical details.
The traditional image of a devil had cloven hooves, like a goat. So most likely that root resembles a goat's foot, hence the name.